A surprising discovery about how brain cells handle sugar could shift how scientists approach dementia and Alzheimer’s ...

New research reveals that sugar metabolism in brain cells may be a crucial defense against Alzheimer’s and related dementias.

Frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are neurodegenerative disorders with an onset age typically lower than 65 years. The prediction and diagnosis of FTLD ...

Clinical functional assessments were performed in all patients at pre-specified timepoints over the course of the study using validated tools, including the Clinical Dementia Rating - Frontotemporal ...

Scientists have discovered a new protein pathway involved in neurodegeneration by studying “mini-brain” organoids made from patients with frontotemporal lobar degeneration (FTLD).

New insights into neurodegeneration using human 'mini brains' Research findings could lead to treatments for frontotemporal lobar degeneration and Alzheimer's Date: April 9, 2025 Source: Ohio ...

Research findings could lead to treatments for frontotemporal lobar degeneration and Alzheimer’s ...

"Studies have shown that vulnerability to Alzheimer's-related changes in the brain increase in women from pre- to post-menopause. And so, while menopause broadly might be an important factor that ...

Although blood-based biomarkers for detection of AD pathology are becoming more readily available, their clinical value is unclear when utilized for frontotemporal lobar degeneration syndromes ...

Alzheimer's pathology in syndromes related to frontotemporal lobar degeneration correlated with worse cognitive performance.

Elucidation of the mechanism behind frontotemporal lobar degeneration Loss of VCP gene function during neural development causes the disease Peer-Reviewed Publication Toho University image: ...

Itching and scratching occur early and more often among patients with frontotemporal lobar degeneration vs those with Alzheimer disease. Patients with vs without itching exhibit severe brain atrophy ...