Human de novo mutation rates from a four-generation pedigree reference The DNA of each child that is born contains entirely new mutations, not found in either of their parents. To find out how ...

The study is described in a new paper that was published in Nature titled “Human de novo mutation rates from a four-generation pedigree reference.” As explained in the paper, the researchers ...

We studied a four-generation autosomal-dominant pedigree to identify disease loci for keratoconus. Methods: A two-stage genome-wide scan was applied to 27 family members. First linkage analysis ...