Fibrous dysplasia is a rare, mosaic disorder that leads to fractures, pain, and disability. Gain-of-function GNAS variants alter skeletal stem-cell differentiation, which results in the formation ...

Bone turnover, a process in which old bone is continuously replaced with new bone, is unusually accelerated in fibrous dysplasia and contributes to bone abnormalities.

A 21-year-old man had received a diagnosis of fibrous dysplasia and the McCune–Albright syndrome at 3 years of age, after a bone fracture. Throughout childhood, he had progressive skull ...

A clinical trial at the National Institutes of Health found that a medication, denosumab, significantly reduced abnormal bone turnover in adults with fibrous dysplasia, a rare disease marked by ...

This article will cover a range of reasons why a person may have shin pain, including symptoms, treatments, ... According to the AAOS, around 7% of all benign bone tumors are fibrous dysplasia.

SAN FRANCISCO — The presence of fibrous dysplasia alone, without associated visual loss, is not sufficient to warrant prophylactic decompression of the optic nerve, surgeons here advise.

Emanuel has polyostotic fibrous dysplasia, a rare bone disorder where scar-like tissue forms instead of bones. Sometimes large tumors, which are benign, develop, too.

Adamantinoma of long bones and osteofibrous dysplasia are rare, osteolytic primary bone tumours of uncertain origin containing areas of fibrous and fibro-osseous proliferation. We investigated the ...

The bone fragment, which comes from the famous archaeological cave site of Krapina, ... "Fibrous dysplasia in a 120,000+ year old Neandertal from Krapina, ...