Abstract:        Obesity, a growing global issue, has been closely associated with an increased risk of various cancers, especially breast cancer. El ...

The Itovebi (inavolisib)-based regimen reduced the risk of death by more than 30% in people with PIK3CA-mutated HR-positive, HER2-negative advanced breast ...

Supported by Pfizer in collaboration with Arvinas Estrogen Receptor. Disclosure forms provided by the authors are available with the full text of this article at NEJM.org. We thank the patients ...

But eventually, the cancers were expected to mutate and defy the standard drugs, often by altering their estrogen receptor so it signals the cancer cells to grow without ever binding to estrogen.

Estrogen Receptor Subtypes & Bioidentical Estrogens Estrogen-receptor subtypes may influence how various estrogens act in different tissues. Estradiol binds equally to estrogen receptors α and ß ...

Nat Clin Pract Oncol. 2008;5(9):531-542. The authors declared no competing interests. Cite this: The Role of Hormonal Therapy in the Management of Hormonal-Receptor-Positive Breast Cancer With Co ...

Marni Rose McFall is a Newsweek reporter based in London, U.K. Her focus is on internet trends, U.S. politics and popular culture. She has covered fashion, culture, art and music extensively.