This study offers useful findings demonstrating the cartilage-protective effects of osteoactivin in inflammatory experimental models. The study provides compelling evidence that osteoactivin may serve ...

A new study published in Cancer Cell reveals that blocking a key nutrient-scavenging process in pancreatic tumors reprograms the tumor microenvironment—reducing fibrosis, enhancing T cell infiltration ...

In this valuable study, the authors provide a simple yet elegant approach to identifying therapeutic targets that synergize to prevent therapeutic resistance in ovarian cancer using cell lines, ...

Pancreatic cancer is often diagnosed at an advanced stage and is characterized by a poor prognosis and rising mortality.

Low intensity pulsed ultrasound (LIPUS) inhibited chondrocyte senescence and the secretion of senescence-associated secretory phenotype factors CCL4 and CCL2 by regulating the PI3K/AKT/mTOR signaling ...

Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect ...

Most existing risk assessment methods lack the capability to conduct large-scale analysis and accurately evaluate long-term trends. To solve this problem, this study integrated various methodologies, ...

Our genes underlie all aspects of life, from our looks to how our cells behave. This includes diseases, as genetic changes can underlie the development and progression of certain health problems. This ...

By creating artificial aging in mice, researchers at Lund University in Sweden have been able to track the formation of aneurysms in the walls of blood vessels.