This study offers useful findings demonstrating the cartilage-protective effects of osteoactivin in inflammatory experimental models. The study provides compelling evidence that osteoactivin may serve ...

A new study published in Cancer Cell reveals that blocking a key nutrient-scavenging process in pancreatic tumors reprograms the tumor microenvironment—reducing fibrosis, enhancing T cell infiltration ...

In this valuable study, the authors provide a simple yet elegant approach to identifying therapeutic targets that synergize to prevent therapeutic resistance in ovarian cancer using cell lines, ...

Pancreatic cancer is often diagnosed at an advanced stage and is characterized by a poor prognosis and rising mortality. Galectin-3 (Gal-3), a chimeric protein, plays a multifaceted role in driving ...

Democratic socialist Zohran Mamdani shocks the establishment by winning NYC's mayoral primary with progressive policies, endorsed by Sanders and AOC, signaling a leftward shift.

By synthesizing recent findings, we elucidate the molecular mechanisms underlying LGALS1’s context-specific effects and its influence on key signaling cascades. These insights aim to provide a ...

This review focuses on recent evidence identifying the roles of the ERK signaling pathway in regulating Schwann cell differentiation, myelination, and remyelination. In addition, the crosstalk between ...

JAK/STAT pathway: The JAK/STAT pathway is a critical cell signaling mechanism that transmits information from cytokines, growth factors, and hormones at the cell surface directly to the nucleus to ...

A new scientific review published in Neuropharmacology explores how the environment interacts with brain biology in shaping personality disorders. By examining molecular, neurochemical, and metabolic ...

The FGF15/FGFR4/ERK signaling pathway was notably activated in the skeletal muscle tissues of nobiletin-supplemented mice, suggesting a protective effect against muscle atrophy despite the pathway’s ...