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This study offers useful findings demonstrating the cartilage-protective effects of osteoactivin in inflammatory experimental models. The study provides compelling evidence that osteoactivin may serve ...
A new study published in Cancer Cell reveals that blocking a key nutrient-scavenging process in pancreatic tumors reprograms the tumor microenvironment—reducing fibrosis, enhancing T cell infiltration ...
In this valuable study, the authors provide a simple yet elegant approach to identifying therapeutic targets that synergize to prevent therapeutic resistance in ovarian cancer using cell lines, ...
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News-Medical.Net on MSNGalectin-3 identified as key driver of chemoresistance in pancreatic cancer
Pancreatic cancer is often diagnosed at an advanced stage and is characterized by a poor prognosis and rising mortality. Galectin-3 (Gal-3), a chimeric protein, plays a multifaceted role in driving ...
Democratic socialist Zohran Mamdani shocks the establishment by winning NYC's mayoral primary with progressive policies, endorsed by Sanders and AOC, signaling a leftward shift.
By synthesizing recent findings, we elucidate the molecular mechanisms underlying LGALS1’s context-specific effects and its influence on key signaling cascades. These insights aim to provide a ...
This review focuses on recent evidence identifying the roles of the ERK signaling pathway in regulating Schwann cell differentiation, myelination, and remyelination. In addition, the crosstalk between ...
JAK/STAT pathway: The JAK/STAT pathway is a critical cell signaling mechanism that transmits information from cytokines, growth factors, and hormones at the cell surface directly to the nucleus to ...
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PsyPost on MSNScientists explore molecular links between stress, brain function, and personality disorders
A new scientific review published in Neuropharmacology explores how the environment interacts with brain biology in shaping personality disorders. By examining molecular, neurochemical, and metabolic ...
The FGF15/FGFR4/ERK signaling pathway was notably activated in the skeletal muscle tissues of nobiletin-supplemented mice, suggesting a protective effect against muscle atrophy despite the pathway’s ...
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