Learn how CD34+ stem cells may help heart attack patients recover. A look at cutting-edge cell therapies and what's coming ...

Here, we show that forcing a metabolic change in embryonic stem cells (ESCs) promotes a developmental identity that better approximates the inner cell mass (ICM) of the early mammalian blastocyst in ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

Researchers have developed the first vascularized organoid model of pancreatic islet cells, which promises to improve ...

Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies.

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas.

Model more closely replicates natural environment of the pancreas, which will be essential for studying diabetes and ...

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting ...

Pulmonary artery endothelial cell (PAEC) dysfunction is a hallmark in the pathogenesis ... For the glycolysis assay, cells were glucose starved in XF assay medium in a CO 2-free XF prep station and ...

This study presents an important practical modification of the orthogonal hybridization chain reaction (HCR) technique, a promising yet underutilized method with broad potential for future ...

TP53 mutations in AML confer resistance to CAR T-cell therapy through exhaustion of CAR T-cells, and dysregulation of the mevalonate and Wnt pathways in AML and CAR T-cells, respectively. Targeting ...

Human umbilical vein endothelial cells (HUVECs) and U251 cells were purchased from the Cell Resource Center, Peking Union Medical College (PCRC). U251 cells were cultured in complete medium consisting ...