There was an Earthworm Jim cartoon back in 1995, which ran for only two seasons and saw Dan Castellaneta (Homer Simpson himself) voicing the title character.

Earthworm Jim Creator Teams with Interplay to Create Sequel, Cartoon, Film Aaron Linde April 22, 2008 2:44 PM 4 ...

Earthworm Jim for iPhone That sets the tone for a combat-filled 2D platform game that includes characters called Bob The Killer Goldfish, Princess What’s-Her-Name and Queen Pulsating, Bloated ...