Get Instant Summarized Text (Gist) A peptide metabolite, Ac-Tβ1-17, derived from thymosin β4, exhibits both strong antiviral activity by inhibiting COVID-19 M pro protease (>85%) and promotes ...

A First-in-Class Hydrolysis-Activated Liver-Targeted THR-β Prodrug Demonstrating A Dual Advantage of Fat Reduction and Muscle Preservation While GLP-1 receptor agonists (e.g., semaglutide ...

A judge called for immediate action on knife crime after jailing another teenager for the fatal stabbing of a man with a weapon she described as a “fearsome machete”. Killer Rhys Hedges ...

While GLP-1 receptor agonists (e.g., semaglutide, tirzepatide) face challenges in sustained weight control and muscle preservation, CG-0416 employs precision targeting of complementary metabolic ...

CG-0416 enhances GLP-1-mediated hepatic lipid oxidation while activating the IGF-1/Akt/FOXO3a axis to suppress muscle catabolism. 2. Oral Administration Potential With 92% oral bioavailability ...

This dual-action profile positions it as a potentially transformative therapy for glaucoma, and we are excited to move it forward into clinical development." "Most current glaucoma therapies focus ...

Hampshire police are taking part in a national week of action that aims to tackle the menace of knife crime. Operation Sceptre, which runs until Sunday, May 25, is a multi-agency initiative ...

Police have raided a Wolverhampton business suspected of being a brothel, as part of an operation targeting anti-social behaviour, exploitation and gang activity. A number of people at the ...

The lockup is as solid as it gets with OTF knives. In my experience, there is always going to be a slight bit of wiggle, just by the nature of the design. The knife was very sharp right out of the ...