we constructed a set of four foldamers with a similar backbone but different substituents and aimed at dissecting the folding and self-association mechanisms of a double-helical foldamer with ...

Second, with heterodyne detection, chiral SFG gives an opposite-signed spectral response useful for distinguishing native (D-) right-handed double helix from non-native (L-) left-handed double helix.

Since the discovery of DNA’s elegant double helix in 1953, scientists have grappled with the challenge of studying these tiny genetic molecules. To see and understand different types of DNA ...