"It's the same for DNA, and the transposon transfer mechanism takes advantage of this." The transposase protein unwinds and separates the transposon's DNA strands first, which makes it easier to ...

A group of researchers, lead by Vasily M. Studitsky, professor at the Lomonosov Moscow State University, discovered a new mechanism of DNA repair, which opens up new perspectives for the treatment ...

A research team from the University of California (UC), Irvine, has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged.

More information: "Unraveling the Base Excision Repair Mechanism of Human DNA Glycosylase," J. Am. Chem. Soc., Article ASAP, DOI: 10.1021/jacs.5b01449 Journal information: Journal of the American ...

Transposon said its oral small molecule TPN-101 has been selected for testing as part of the HEALEY ALS platform trial.

small DNA sequences that travel through the genomes, can silence the genes adjacent to them by inducing a molecule called antisense RNA. This is a new mechanism for evolution that has been unknown ...

R esearchers from the Kind Group have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after ...

The dcr-1 gene seems to play a crucial role in the mechanism. During the study, Sylvia Fischer also discovered how new transposons can arise. If a transposon jumps out of the DNA a hole remains in ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms.

The hypothesis was that during sleep, a process occurs inside individual neurons whereby DNA damage accumulated in waking hours can be repaired. Utilizing a high-resolution microscope that allowed ...