The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

The antibody-DNA conjugate contained one antibody associated with three oligonucleotides for signal amplification. The antibody in the conjugate can recognize the surface tumor antigens of TAEs.

This study provides important new insights into the contributions of local DNA features to the complex molecular mechanisms ... indicative of having more than one amplification event. Inference came ...

Then, it was mixed with 50 nM template sequences, 1 μL of DNA polymerase, 1 μL of endonuclease ... indicating that the EXPAR-mediated signal amplification process has not been initiated. The ...

The resulting target sequence scaffold oligonucleotides were then subjected to a final amplification with 2× ... sgRNA background condition represents signal resulting from complemented NLuc that is ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Edward Haynes reveals how advanced sequencing technologies are assisting food companies in their mission to deliver quality ...

In summary, enalapril significantly mitigated multiple pathological markers associated with aging, including lipid droplets, amyloid, glycogen deposition, and fibrosis, in the brain, kidneys, liver, ...

Comparison of that ancient DNA with modern human DNA showed that the two species had interbred and that people today still carry the genetic fingerprint of that intermixing. Since then ...