Amazon Prime Day may be over, but you can still find some incredible markdowns The biggest shopping event of the season is ...

By incorporating DNA base pairing, electrostatic repulsion, and DNA-nanoparticle interactions, the models aligned with experimental observations and provided a predictive framework for tuning ...

This technique, called volumetric DNA microscopy, creates a 3D image of an entire organism from the inside out, giving scientists an unprecedented view of genetic sequences and where they are ...

Z-crRNA can guide CRISPR-effectors SpCas9 and LbCas12a to cleave specific DNA through non-Watson–Crick base pairing and boost cleavage activities compared to A-crRNA. Z-crRNA can also allow for ...

An elegant method that fuses single-stranded DNA to each motor links them together through complementary DNA base pairing and tracks the motor pairs by two-color total internal reflection fluorescence ...

Typically, PNAs bind to targeted miRNAs via a complementary DNA base pairing system, and this structure is enzymatically stable. However, compared to classical PNAs, serine-gamma PNAs (γPNAs), with ...

A fundamental concept for understanding the structure of DNA as well as the chemical process of DNA replication involves specific hydrogen bonding interactions made between these complementary ...

Specifically, we performed 1 μs MD simulations using explicit water and evaluated a variety of characteristics, such as variations in major and minor groove widths measured by the phosphorus to ...

The recent development and optimizations of base editors, rubber and pencil genome editing tools now promise to enable direct functional assessment of SNVs in model organisms. However, the lack of ...

Investigations of genome defense mechanisms in the model filamentous fungus Neurospora crassa, reported by Rhoades et al. (4), give credence to the biological significance of pairing between intact ...