These bacteria can metabolize nutrients and complex carbohydrates. They also make cholesterol-dependent cytolysin-like (CDCL) toxins, which can poke holes in other microbes, causing them to die. But ...

The bacteria are also fierce protectors of their own turf. They produce proteins called cholesterol-dependent cytolysin-like (CDCL) toxins that punch holes in rival bacteria, causing them to burst ...

The bacteria are also fierce protectors of their own turf. They produce proteins called cholesterol-dependent cytolysin-like (CDCL) toxins that punch holes in rival bacteria, causing them to burst and ...

Led by microbiology professor Rodney Tweten, the team studied Bacteroides bacteria, which produce cholesterol-dependent cytolysin-like (CDCL) toxins. These proteins help bacteria compete in the ...

Yet it remains challenging to measure the amplitudes and time scales of protein motions. Here we show that the cytolysin A (ClyA) nanopore was used as a molecular tweezer to trap a single ...

The innate immune response constitutes the first line of defence against pathogenic microorganisms. Phagocytes, such as macrophages and neutrophils, engulf microorganisms into a vacuole or ...

Lysosomes are dynamic organelles that receive membrane traffic input from the secretory, endocytic, autophagic and phagocytic pathways. They can also fuse with the plasma membrane. Live-cell ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The correlation of individual conformational changes in dynamic protein complexes ...

Section of Digestive Diseases and Nutrition, University of Illinois at Chicago and Chicago Veterans Administration Medical Center (West Side Division), Chicago, IL, USA Correspondence to: Dr G Hecht, ...

To understand the breadth of enterococcal diversity, we examined little-sampled (non-clinical, non-human) environments, including those minimally impacted by human habitation or pollution. To maximize ...