“Stopping medications for Crohn’s disease can result in complications ... bowel perforation, fistula, stricture formation, toxic megacolon, or abscess, or secondary infectious colitis.

In contrast to ulcerative colitis, the inflammation in Crohn's disease is typically transmural, segmental and can give rise to complications as a result of fibrosis, stricturing and fistulising (1).

Anti-TNFa are the most studied drug for perianal Crohn’s disease. • Some studies conclude that women had a longer fistula closure time than men. • Few data corroborate the difference between sexes in ...

Anal fistulas can be painful and persistent. Here’s what causes them and the best treatment options to manage or eliminate ...

But Farhadi says that for people with Crohn’s disease, NSAIDs can further aggravate ulcer formation or the inflammatory process. Instead, people with Crohn’s disease may find relief with ...

or a decrease in fistula discharge of more than 50% in at least four patients. Over the next 24 months, the company envisages expanding its stem cells trial from Crohn’s disease, to other inflammatory ...

It is therefore important to identify the risk factors for nephrolithiasis. Inflammatory bowel diseases, which include Crohn’s disease, represent a risk factor for the formation of renal calculi, due ...

The fourth key factor involves disease progression mechanisms. IBD progresses through distinct patterns depending on the specific type. The two primary forms, Crohn’s disease and ulcerative ...

Background: Literature on the association between high infliximab (IFX) trough levels and perianal fistula response in pediatric patients with perianal fistulizing Crohn's disease (PFCD) is limited.

It is estimated that approximately 50% of patients with Crohn’s disease develop fibrosis of the GI tract, resulting in stricture (stenosis) formation and intestinal obstructions, most frequently ...

like a fistula or a connection, those could be a differentiator from Crohn’s disease. But in the current era, often what we’re really thinking about when we’re thinking about starting a ...