Over 250 associations between phenotype and copy number variation were identified. New ties were revealed between certain genes and various traits, like height. For example, some carriers of very rare ...

More information: Jonathan Wilson et al, Copy number variation contributes to parallel local adaptation in an invasive plant, Proceedings of the National Academy of Sciences (2025). DOI ...

Impact of overfixation on actionable biomarkers and checkpoint inhibitor (CKI) targets with immunohistochemistry (IHC) in a patient population with non-small cell lung cancer (NSCLC). This is an ASCO ...

Scientists at the Institut Pasteur and McMaster University have discovered that the evolution of a gene in the bacterium that causes bubonic plague ...

We estimated tumor fraction (TFx) and detected copy-number alterations (CNAs) using ichorCNA. Presence of 8q amplification was further analyzed using the likelihood ratio test (LRT). Eleven patients ...

However, ES is not the first choice for detecting copy number variants (CNVs), which are typically deletions or duplications of DNA segments. CNVs cause a significant proportion of genetic disorders.

This new product is the only single-cell high-throughput solution for measuring genome-wide copy number variants (CNVs) on the market and is designed to fulfill important needs in the critical ...

The extensive de novo copy-number gains suggested the significance of copy-number variation during embryogenesis, the researchers noted. "The intracranial fetus-in-fetu is proposed to arise from ...

“Given the key role of AMY1 copy number variation in human evolution, this genetic variation presents an exciting opportunity to explore its impact on metabolic health and uncover the mechanisms ...