Osteocytes live in fluid-filled hollows within the bone matrix and are interconnected by fingerlike extensions through microscopic tunnels.

Osteocytes are the master regulators of bone health, sensing mechanical forces and directing when to build or break down bone. But when exposed to senescent cells—damaged cells that stop ...

Chewing, or mastication, is thought to impact jawbone structure as bone is continually reconstructed along with alterations in mechanical load. However, the underlying mechanisms are unknown.