Objective Faecal microbiota transplant (FMT) effectively treats recurrent Clostridioides difficile infection (rCDI), but its mechanisms of action remain poorly defined. Certain bile acids affect C.

The incidence of C. difficile trended downward from 5.76 per 10,000 patient-days to 5.65, but did not reduce enough to garner statistical significance.

INTRODUCTION. Clostridium difficile, a gram-positive spore-forming anaerobic bacterium, is one of the leading pathogens that cause nosocomial infections []. Clostridium difficile infection (CDI) is ...

Box 1. Guidelines for current treatment of Clostridium difficile infection. Antiperistaltic agents and opiates should be avoided. In general, strive to use antibiotics covering a spectrum no ...

Table 5. Classification of Severity of Clostridium difficile Disease a Severity Classification Ref. 18 Ref. 21 Ref. 48; Mild or moderate: WBC count of ≤15,000/μL or SCr conc. of <1.5 times baseline ...

Hypovolemia Pathophysiology. Normally, your body is made of about 50%-60% fluid, including water, blood, and lymphatic fluid. When your fluid levels are out of balance (too high or too low ...

INTRODUCTION. Diverticulitis is the most common clinical complication of diverticular disease, affecting 10-25% of patients with this pathology 1.Small lumen pockets, primarily from the colon region ...

Health Canada approved fecal transplants for recurrent Clostridium difficile (C. difficile) infections in 2015. Impacting the colon, these infections lead to diarrhea and, if recurring ...

Exacerbations of COPD are thought to be caused by complex interactions between the host, bacteria, viruses, and environmental pollution. These factors increase the inflammatory burden in the lower ...

A panelist discusses how immune thrombocytopenia (ITP) is characterized by isolated low platelet counts due to autoimmune destruction, with classification based on duration (acute, extended, or ...