News

pharmaphorum3d
Lilly's tau drug for Alzheimer's flunks phase 2 test
inhibitor – failed a phase 2 study in early symptomatic Alzheimer's. The experimental therapy didn't meet the primary endpoint of decreasing the change from baseline measured by the integrated ...
pharmaphorum3d
Levicept says non-opioid drug cuts arthritis pain in phase 2
A non-opioid drug for pain developed by UK biotech Levicept, with a new mechanism of action, has shown it can reduce pain associated with osteoarthritis in a phase 2 trial. Neurotrophin-3 (NT-3 ...
politicsweb5d
Cost of delayed Lesotho Highlands Phase-2 balloons by R11bn – DA
A Democratic Alliance Parliamentary Question has revealed that the cost of Phase II of the Lesotho Highlands Water Project (LHWP) has ballooned from R42.1 billion to R53.3 billion in just over a year ...
BMJ4d
A phase I, open-label, multicentre, first-in-human study to evaluate safety, pharmacokinetics and efficacy of AMG 404, a PD-1 inhibitor, in patients with advanced solid tumours
and 4.4 (2.2–9.7) months for Cohorts 1–5 (any tumour type), Cohort 6 (selected immunosensitive tumour types), Cohort 7 (MSI-H tumours) and Cohort 8 (NSCLC/PDL1-H), respectively (online supplemental ...
The Lancet6d
Efficacy of anifrolumab across organ domains in patients with moderate-to-severe systemic lupus erythematosus: a post-hoc analysis of pooled data from the TULIP-1 and TULIP-2 ...
cCentre for Epidemiology Versus Arthritis, The University of Manchester and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health ...