Treatment consisted of oral decitabine 35 mg plus cedazuridine 100 mg on days 1–5 and venetoclax (variable doses of 100–400 mg, day 1 to 14, 28-day cycle). The primary outcomes were safety for the ...

In phase 1, 75% of patients had also received chemotherapy whereas only 31% had in phase 2. In the phase 1 portion of the trial, ARV-110 doses ranged from 35–700 mg QD or 210–420 mg BID. Based on ...

Thus, the recommended phase 2 dose was 600 µg of SHR-1501 + 120 mg of BCG. Grade 3 or worse treatment-related adverse events (TRAEs) were reported in 1 patient (12.5%) receiving SHR-1501 alone ...

Malhotra J, Nikolinakos P, Leal T, Lehman J, Morgensztern D, Patel JD, et al. A phase 1–2 study of rovalpituzumab tesirine in combination with nivolumab plus or minus ipilimumab in patients with ...

We conducted a multicohort, open-label, phase 1/2 trial (CC-220-MM-001) at 42 treatment centres in Europe, Canada, and the USA. Patients aged 18 years or older with multiple myeloma who had received ...

Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (the "Company") today announced that results from the Phase 1/2 study (KL264-01/MK-2870-001) evaluating the novel TROP2 antibody drug conjugate (ADC) ...

Topline Data from the Phase 1/2 FORTITUDE™ Dose Escalation Cohorts. The FORTITUDE™ clinical development program includes a randomized, placebo-controlled, double-blind, ...

Dive deep into the Star Wars universe with a full breakdown of every single Clone Trooper Battalion, Legion, and Corps. From iconic units like the 501st to lesser-known divisions, this guide ...

The crash was reported shortly after 2 a.m. Sunday, June 8, on the southbound side of I-95 just north of Maryland Route 100 in Howard County, according to Maryland State Police. An on-duty Maryland ...

According to state police, the crash occurred around 2:02 a.m. in the area of southbound I-95, north of Maryland 100 in Howard County, when an on-duty state trooper’s unmarked vehicle was struck.

1 Introduction. The coronavirus disease of 2019 (COVID-19) is a highly contagious and disastrous disease that has been declared a global pandemic since early 2020 ().COVID-19, which is caused by ...

Clone Troopers wore more than just standard Phase I and Phase II armor some had unique, customized, and highly specialized designs that set them apart. In this video, we explore the most unique ...