Clonal hematopoiesis (CH) is an age-related process characterized by mutations in hematopoietic stem/progenitor cells (HSPCs), most commonly in the DNMT3A gene. In CH, mutant HSPCs gain a ...

This work is published in Nature in the article, “Clonal tracing with somatic epimutations reveals dynamics of blood ageing.” In youth, humans have between 50,000 to 200,000 active blood stem ...

Panelists discuss how to approach second-line therapy decisions for patients with metastatic breast cancer, emphasizing the importance of biomarker testing, including ESR1 mutations, and considering ...

"On Friday, he was diagnosed with prostate cancer, characterized by a Gleason score of 9 (Grade Group 5) with metastasis to the bone." "While this represents a more aggressive form of the disease ...

Former President Joe Biden was diagnosed with an "aggressive form" of prostate cancer that has a five-year survival rate of between 30% and 40%. The former president's prostate cancer is ...

The former president’s prostate cancer is characterized by a Gleason score of 9 and Grade Group 5 with bone metastasis, indicating that it is “pretty far advanced,” Fox News senior medical ...

LVI serves as an early indicator of metastasis for doctors. Currently, it can solely be detected by “examining tissue surrounding the tumor that has been surgically removed.” It added that the ...

The Melanoma Institute of Australia (MIA) previously developed a risk calculator for sentinel lymph node (SLN) metastasis risk to help clinicians and patients with primary cutaneous melanoma ...

On Friday, he was diagnosed with prostate cancer, characterized by a Gleason score of 9 (Grade Group 5) with metastasis to the bone," the statement said. While the cancer is considered highly ...