TI-CH remodeled the tumor immune microenvironment and accelerated tumor organoid growth, findings that support a role for an aging-related hematologic clonal proliferation in cancer evolution.

The authors discuss both the practical and theoretical limitations of the clonal model of cancer evolution and suggest ways to enhance its relevance and accuracy. Cancer cells are driven by the ...

Researchers published a new study, “Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution,” in Cell that they say solves the mystery of what drives the genomic ...