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Broad Institute researchers have developed a way to edit the genetic sequences at the root of Huntington's disease and Friedreich's ataxia.The ...
Single-cell analysis of over 120,000 cells reveals how mitochondrial DNA mutations accumulate with age and may affect ageing and neurodegeneration.New ...
The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...
A London-based start-up employs bioprospectors to scour the world for DNA to feed AI models building a digital tree of life ...
5d
AZoLifeSciences on MSNEpigenome Editing: Enhancing Endonuclease Protein Design for In Vivo ApplicationsResearchers have engineered a compact, high-specificity IscB variant, NovaIscB, for safe, persistent in vivo epigenome ...
Industrial fermentation using bacteria, yeast and other microbes to produce specific products has the potential to reduce ...
A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...
In a discovery three decades in the making, scientists at Rutgers and Brookhaven National Laboratory have acquired detailed ...
A study introduces a CRISPR model that predicts gRNA activity more accurately using chemically synthesized gRNAs. The model ...
BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...
Researchers have uncovered that some childhood cancers have a substantially higher number of DNA changes than previously ...
Boys who gain excess weight during puberty may cause gene changes in future children, raising their risk for obesity and poor ...
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