Scientists have developed a chemical method to reverse aging in human cells without the need for genetic modification.

Download this article to explore how scientists engaged in early cancer diagnostics research can maximize methylation sequencing workflows using cutting edge methylation detection and custom capture ...

Urinary cell-free DNA (ucfDNA) analysis offers a non-invasive alternative, with DNA methylation patterns providing a promising avenue for identifying tumor-derived cfDNA. This study explores the ...

Scientists have developed an improved technique to comprehensively profile DNA methylation in single cells, an advance that will help researchers better study the role of epigenetics in cancer and ...

More information: Hua Bao et al, Early detection of multiple cancer types using multidimensional cell-free DNA fragmentomics, Nature Medicine (2025). DOI: 10.1038/s41591-025-03735-2 ...

Methods: Herein, we employed a multimodal analysis approach, namely SPOT-MAS (Screen for the Presence of Tumor by DNA Methylation and Size), to profile alterations in methylation and fragment length ...

Conventional Cell-Based versus Cell-Free Gene Synthesis. Conventional cell-based gene synthesis requires a more complicated, time- and resource-intensive workflow to assemble, sequence, amplify, and ...

More information: Sandhya Malla et al, The scaffolding function of LSD1 controls DNA methylation in mouse ESCs, Nature Communications (2024). DOI: 10.1038/s41467-024-51966-7 ...

Aldevron unveiled Alchemy™ cell-free DNA technology. The technology was designed to support development and preclinical programs, with a future cGMP offering expected to launch in 2025 to ...

Singlera is at the forefront of innovation with its proprietary technologies in single-cell sequencing, DNA methylation, and bioinformatics, making significant strides in the global field of genomics.