A groundbreaking blood test can detect multiple cancers early with high accuracy using cell-free DNA analysis.

Cell-free DNA (cfDNA) circulating in the bloodstream ... nucleosome positioning, and inferred methylation profiles. Bioinformatic pipelines were standardized across all phases.

Cell-free DNA (cfDNA) analysis is transforming ... Epigenomic alterations, such as DNA methylation and fragmentation patterns (fragmentomics), provide critical insights into tumorigenesis and ...

The evidence was revealed in a new study by scientists from the Institute of Genetics and Developmental Biology of the ...

A reflex ctDNA-methylation MCED test can detect multiple cancer types in patients with obesity, a new study suggests.

Multicancer early detection tests are revolutionizing cancer screening by using liquid biopsies to screen for multiple ...

Laboratory for MEMS Applications, IMTEK─Department of Microsystems Engineering, University of Freiburg, 79110 Freiburg, Germany Division of Cancer Genome Research, German Cancer Research Center (DKFZ) ...

Despite high specificity, the tests show low sensitivity for early-stage cancers, necessitating further validation through ...

DNA ‘barcodes’ shed light on how the blood ages - The discovery could help prevent diseases years before symptoms appear, as ...

Material and methods: We analysed DNA methylation in TCGA-OSCC to identify genes with high methylation levels in tumor vs matched non-tumor tissue. Cell-free DNA (cfDNA) methylation levels of selected ...