A new review published in Genes & Diseases explores the multifaceted role of FAM20C, a Golgi protein kinase, in disease ...

This new review article highlights the crucial role of GATA6, a transcription factor, in pancreatic ductal adenocarcinoma (PDA). The article explores ...

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

Pulmonary hypertension, despite advances in treatment, still has a poor prognosis, which is often associated with right heart failure, and for which pulmonary arterial hypertension (PAH) is a severe ...

The integration of cytokines into stem cell and organoid research has significantly advanced drug discovery by enabling more ...

[35] Johnstone, Ruefli, and Lowe (2002) Apoptosis: a link between cancer genetics and ... via activation of p38 pathway and inhibit proliferation and migration of bone marrow mesenchymal stem cells.

In the present study, we investigated the functional link between miR-17-92 cluster and Wnt ... Finally, we found that low doses of LiCl promoted the proliferation of ICP2 and DF1 cells, while high ...

Deregulated apoptosis may also be the leading cause ... 11 and -12), which allow for interactions with other proteins, and link with signalling pathways. In another study, the sensitivity of NSCLC and ...

And the increased ratio could be a landmark of the early stage of apoptosis ... and SW1990 cells significantly inhibited tumor cell viability compared to Gemcitabine alone (Figure 7E). These results ...

These immature myeloid cells inhibit the proliferation and induce apoptosis of activated T cells. Targeted depletion of granulocytic MDSC (Gr-MDSC) in autochthonous PDA increases the intratumoral ...