Z-VAD-fmk blocks hippocampal neuronal loss. The peptide z-VAD-fmk is a broad-spectrum caspase inhibitor that effectively delays apoptosis in many cell types 14,15,16.To assess its potential ...

Amerimmune LLC Maintains Intellectual Property on the COVID-19 Related Use of Caspase Inhibitors as a Result of Histogen Inc. Led Arbitration January 18, 2023 02:02 PM Eastern Standard Time ...

TREAT-ME 1: Treatment of advanced gastrointestinal cancer in a clinical phase I/II trial with genetically modified mesenchymal stem cells: Clinical results of a phase I study. An open-label, ...

SAN DIEGO, April 09, 2018 (GLOBE NEWSWIRE) -- Conatus Pharmaceuticals Inc. (NASDAQ:CNAT), a biotechnology company focused on the development of ...

Caspase-1 leaves the inflammasome and goes off to activate several cytokines, including IL-1β (4), as well as a protein called gasdermin-D (not pictured), which causes cells to explode and ...

Eyedrops with a caspase-9 inhibitor prevent retinal injury from retinal vein occlusion. In the left image, RVO causes swelling in the retina and the retinal layers are less distinct. In the right ...

Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark of apoptosis initiation—with fluorescent dyes. Researchers often perform multiplex caspase assays ...