Targeted Oncology connects oncology professionals with updates on immunotherapy, biomarkers, cancer pathways, and targeted ...

On June 3, 2025, the industry's first proof-of-concept clinical validation of AI-driven drug discovery was published in Nature Medicine. Insilico Medicine and collaborators reported promising safety ...

A research team led by Korea University professor Hugh I. Kim, also known as Kim Joon-gon in Korean, has succeeded in developing an inhibitor that blocks Alzheimer’s-causing toxins in ...

Accropeutics’ drug hit the goals of a phase 2 psoriasis trial in China, prompting the biotech to “accelerate” the TYK2/JAK1 inhibitor’s development.

Pan-caspase inhibitor protects against noise-induced hearing loss in a rodent model Maria Fernanda Yepes 1 Kayla Minesinger 2 Federica M. Raciti 3 Maria Camila Salazar 3 Suhrud M. Rajguru 1,2,3 * 1 ...

In Fig. 2 A, there is potential vertical splicing between lanes 1 and 2, and 2 and 3 of the C3 blot, and lanes 2 and 3 of the AP2α blot. The repeated experimental results confirm the depletion of ...

In a 2023 systematic review of clinical studies, Mostaghimi and colleagues found that patients on any JAK inhibitor were nearly four times more likely to experience acne than patients who received ...

Berotralstat is an oral kallikrein inhibitor that has been shown to reduce the frequency of attacks by approximately 45% in a phase 3, double-blind, randomized, placebo-controlled trial 16 and by ...

Caspases are a highly conserved family of cysteine-aspartyl proteases known for their essential roles in regulating apoptosis, inflammation, cell differentiation, and proliferation. Complementary to ...

Intracellular IL-1 beta is an inhibitor of Fas-mediated apoptosis. J Immunol.1996; 157:3949–3957. Crossref Medline Google Scholar 12 Romson JL, Hook BG, Kunkel SL, Abrams GD, Schork MA, Lucchesi BR.