This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...

The rate of fatal non–AIDS-defining cancers was 10 times lower in patients with CD4 counts >500 cells/mm 3 than in those with CD4 counts <50 cells/mm 3. Evidence is accumulating to indicate that ...

How high "should" the CD4-cell count rise in order to minimize AIDS-related morbidity and mortality? To find answers, researchers analyzed clinical data from 16 cohort studies including more than ...

Models were adjusted for CD4 count (immune status) at ART initiation ... of follow-up), and 1166 individuals were not part of the BC Centre for Excellence in HIV/AIDS's DTP. The final sample included ...

S3). Immunohistochemical analysis showed a dense lymphocytic infiltration of the lamina propria positive for T-cell receptor (TCR) α, CD3, CD4, and granzyme B but which did not express TRBC1 ...

Background: In people living with HIV (PLHIV), the CD4/CD8 ratio has been proposed as a useful marker for non-AIDS events. However, its predictive ability on mortality over CD4 counts, and the role of ...

All participants identified in the AIDS-PCIS receive a combination antiretroviral regimen ... Having a complete record of CD4 cell counts to 9–15 months after receiving ART. Ultimately, data from 326 ...

A typical platelet count range can change with age. Platelet counts may fluctuate due to natural vascular aging, changes in bone marrow tissue, and altered blood plasma makeup. Platelets ...

The South African government said it funded the majority of the HIV/AIDS programmes in the country, with a small percentage funded by the private sector. Health minister Aaron Motsoaledi says the ...

AIDS is diagnosed when the CD4 count falls below 200 cells/µl. The profound impact of HIV-mediated destruction on immune function is undeniable. Clinical evidence of the efficacy of Highly Active ...

The move from the UN agency dedicated to ending the disease came in response to an immediate 90-day funding pause for all foreign assistance laid out in an executive order by President Trump, ...