Creative Biolabs expands its complement testing service, elevating sensitivity and efficiency for immunological research. Creative Biolabs' complement C1q binding assay enables scientists to determine ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The complement system and neutrophils ...

An open-label extension study highlights pegcetacoplan's ability to safely and effectively limit geographic atrophy progression. Pegcetacoplan demonstrates a favorable safety and efficacy profile for ...

Nanomedicine shows great promise in drug delivery due to its versatility in drug loading and ability to target the tissue of interest; however, its current applicability is significantly hindered by ...

This fundamental study significantly advances our understanding of how parasites evade the host complement immune system. The new cryo-EM structure of the trypanosome receptor ISG65 bound to ...

This important study advances our knowledge of how parasites evade the host complement immune system. The new cryo-EM structure of the the trypanosome receptor ISG65 bound to complement component C3b ...

This story is part of a series on the current progression in Regenerative Medicine. This piece is part of a series dedicated to the eye, and it marks the second of a three-part series on dry ...

Each pathway converges with the cleavage of complement C3 into C3a and C3b by C3 convertase, and the formation of C5 convertase, which cascades down to C5 convertase, cleaving C5 to C5a and C5b, ...

NovelMed Therapeutics, Inc. announced today topline results from First-in-Human Phase I clinical trial of its complement blocker monoclonal anti-Properdin antibody, known as NM3086. Phase I Clinical ...

With Alzheimer’s disease therapies finally reaching the market and hundreds of active clinical trials for therapies and diagnostics, it seems like every week brings another potential avenue to explore ...

Innate Immunity is a nonspecific host defense mechanism against foreign antigens. It is the first line of defense in a host and occurs immediately or within hours after exposure. This type of immunity ...