The study shows the average monthly C. diff rate before the intervention was implemented in 2015 was 11.94 per 10,000 patient days, that is, the number of days the patient spent in the hospital ...

Gastroenterologists rely on testing to identify C diff infections, and polymerase chain reaction (PCR) tests are largely replacing ELISA assays. "PCR is an excellent, extremely sensitive test for ...

Clostridioides difficile(C. diff) is a bacterium that can infect the large intestine. Antibiotics used to treat it have been traditionally evaluated in a monoculture – not considering ...

C diff brings on diarrhea and colitis, an inflammation of the colon, and is responsible for nearly 500,000 infections annually in the United States. The fight against C diff takes its toll ...

Researchers used the mRNA-LNP vaccine platform — the same that provided the COVID-19 vaccines — to create the C. diff vaccine. “Our approach was to create a multivalent mRNA vaccine that ...

A team of researchers at the University of Pennsylvania took a new approach, using mRNA technology to design a multipronged vaccine that targets several proteins that underlie C. difficile’s ...