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The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...

Epidemiological and genetic evidences have shown that an inflammatory process may contribute to AD pathology. However, the exact relationship and mechanisms are not clear. Therefore, we tried to ...

Background Thrombin is implicated in coronary bypass graft disease; it cleaves its receptor’s extracellular N-terminal domain and unmasks a new N-terminus as a tethered ligand. We studied the effects ...