Recombinant optogenetic and chemogenetic proteins are potent tools for manipulating neuronal activity and controlling neural circuit function ... of Protocadherin 10 to the scaffolding protein PSD-95, ...

“We discovered a full brain circuit that senses inflammation in the bloodstream and sends signals that reduce motivation,” said Adam Kepecs, PhD, professor of neuroscience at WashU Medicin ...

A new study has identified a common brain circuit for intensity of political involvement across the political spectrum. Researchers from Mass General Brigham assessed data from 124 male military ...

Lesions that cause secondary psychosis were most functionally similar to lesions that cause amnesia, though lesions that cause amnesia were more likely to be in the brain’s left hemisphere while ...

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And for first author Tu, the findings offer hope that a better understanding of the brain circuit for motion sickness could also lead to improved medications for his condition. Other contributors to ...

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Coordinates suggested a common brain circuit defined by negative functional connectivity to the right frontal pole. The circuit aligned with creativity changes seen in some neurodegenerative diseases.

“Our study provides the first direct evidence that lesions causing psychosis map to a common brain circuit centered on the hippocampus, particularly the posterior subiculum,” lead author ...

Scientists have discovered a fascinating link between creativity and cognitive impairment. In addition to producing art and literature, creativity is essential for problem-solving and adaptation.

Researchers analyzed data from 857 patients across 36 fMRI brain imaging studies and mapped a common brain circuit for creativity. A new study led by researchers at Mass General Brigham suggests ...

Andrew Pines, MD, MA, a resident in the Department of Psychiatry at Brigham and Women's Hospital and a researcher in the Center for Brain Circuit Therapeutics, is the lead author of a paper ...