Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering ...
Designing BBB organoids posed a technical challenge: growing the two components—the brain ... blood vessels in the BBB. In contrast, blood vessel organoids did not express these molecules before ...
We recently published a list of 10 AI News and Ratings You Should Not Miss. In this article, we are going to take a look at ...
Scientists have developed a lipid nanoparticle system that enables mRNA to cross the blood-brain barrier, a long-standing challenge in n.
The Mt. Sinai study could open the door to future therapies for Alzheimer’s, amyotrophic lateral sclerosis, brain cancer, and ...
The blood–brain barrier acts as a highly selective shield that protects the brain from harmful substances in the bloodstream. However, this same protective feature makes it difficult for most ...
glial cells and the blood-brain barrier following ischemic insult. We also describe the evidence of TRPM2 involvement in these processes, as shown from numerous in vitro and in vivo studies that ...
For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier, a compact layer of cells that protect the brain from ...
The Blood-Brain Barrier Summit will take place online from June 28-30, 2021. This Hanson Wade event is aimed at experts looking to deliver CNS drug candidates safely and successfully across the ...
Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature ...
The study (“Blood–brain-barrier-crossing lipid nanoparticles ... Moreover, these nanoparticles can deliver mRNA to human brain ex vivo samples. “Overall, these BBB-crossing lipid ...