Scientists mapped how the human immune system evolves from birth to old age, revealing key changes that influence health, disease resistance, and aging. Their immune age model could help predict ...

B-cell prolymphocytic leukemia (B-PLL) is a rare, aggressive type of leukemia that progresses rapidly. People with B-PLL typically have a less favorable outlook. However, new targeted treatments ...

Cellular immunity is a protective immune process that ... Using a combination of single-cell RNA sequencing, T cell and B cell receptor sequencing, and mass cytometry analyses, we characterized ...

This important work advances our understanding of the contribution of tissue-resident immune cells to trained immunity phenotypes. The evidence supporting the claims is convincing, with results that ...

However, their role in ensuring long-term immunity or offering an advantage ... application to autoimmune diseases with defective B cell components beyond just lupus, while providing more insights ...

There are many different types of B-cell lymphomas. Treatment usually depends both on the type of lymphoma and the stage (extent) of the disease, but many other factors can be important as well. For ...

Adaptive immunity is highly specific to a given antigen and is highly adaptable. Using a combination of single-cell RNA sequencing, T cell and B cell receptor sequencing, and mass cytometry ...