is a peptide-based therapy designed for systemic lupus erythematosus (SLE). Its mechanism of action revolves around modulating autophagy, a process involved in immune system regulation.
HCQ and chloroquine have a recognised role as DMARDs in the treatment of RA, Sjogren’s disease and systemic lupus erythematosus ... storage disorder due to the inhibition of constitutive autophagy ...
Adicet Bio, Inc. (ACET), a clinical stage biotechnology company, Wednesday said it received Fast Track Designation from the U.S. Food ...
Systemic lupus erythematosus, more commonly known as lupus, has a variety of symptoms and room for improvement when it comes ...
Systemic lupus erythematosus commonly presents as a rash. The rashes are caused by inflammation from the immune system fighting the body. Systemic lupus erythematosus, more commonly known as lupus ...
Interferon-alpha activity may be used routinely in clinical settings as a biomarker for cutaneous lupus erythematosus and ...
An investigator-initiated Phase 1/2 trial of CNTY-101, an investigational therapy, has been announced for the treatment of B-cell mediated autoimmune diseases, including systemic lupus erythematosus ...
“In addition to decreasing the inflammation by decreasing lesional staphylococcus aureus, the mupirocin treatment also lowered skin monocyte levels, which are important in driving cutaneous lupus,” ...
In the Phase 2b CARE study, the investigational drug, cenerimod, demonstrated safe and effective results for treatment of adults with moderate-to-severe systemic lupus erythematosus (SLE). The drug’s ...
EULAR/ACR SLE classification criteria were not linked to mortality or hospitalization, a developed ominosity model adequately predicted mortality.
The odds of developing systemic lupus erythematosus or systemic sclerosis appear to significantly increase with the use of ...
Systemic lupus erythematosus (SLE) often presents with neuropsychiatric (NP) involvement, including cognitive impairment and depression. Past magnetic resonance imaging (MRI) research in SLE patients ...