Although experimental work has helped to unravel some of the principles of atherosclerosis pathophysiology, gaps remain in translation to the clinic, and these breeches require bridging to achieve ...

Coronary atherosclerosis begins with early intimal ... The morphological comparison of the pathophysiology of atherosclerotic plaque progression, as presented in this Review, should help to ...

The understanding of the pathophysiology of atherosclerosis and related vascular diseases has changed over the last decade, providing new perspectives for preventive and therapeutic strategies.

The study hypothesizes that OTUB1 may influence the pathophysiology of VSMCs during atherosclerosis by modulating the stability of proteins like PDGFRβ, a key player in cell proliferation and ...

The pathophysiology of intermittent claudication ... PVD is a sign of generalized atherosclerosis and increases the risk of cardiac morbidity and mortality. Smoking, hypertension, diabetes ...

How Does Atherosclerosis Relate to High Blood Pressure? Atherosclerosis is plaque buildup in the arteries. When it occurs in the arteries that supply blood to the heart, doctors call it ...

Atherosclerosis happens when arteries become narrow and hard due to a buildup of plaque around the artery wall. Atherosclerosis can lead to a heart attack, stroke, and other complications. Other ...

If they become narrower and less flexible because plaque is building up inside them, that's atherosclerosis. It's very risky, because it can lead to a heart attack or stroke. Extra pounds make ...

Prior to 1990, many assumed that once cholesterol plaques form in the arteries causing atherosclerosis, it was not reversible. While this is true for plaques that have calcified, what about ...

You can’t reverse atherosclerosis, but certain medications, dietary changes, and surgery can help to slow its progression and reduce your risk of complications. Atherosclerosis, more commonly ...

A drug candidate, previously successful at treating severe fatty liver disease, reduces atherosclerosis—a primary driver of cardiovascular death worldwide—in large mammals, a study suggests.