Wound healing is a huge challenge for medicine that enhances tissue regeneration and macrophage reprogramming. However, current therapies do not coordinate tissue regeneration and macrophage ...

Extracellular matrix (ECM) stiffness is a key stimulus affecting cellular differentiation, and osteoblasts are also in a three-dimensional (3D) stiff environment during the formation of bone tissues.

Suspecting that autophagy might promote the use of HR over error-prone repair pathways, the research team investigated its effect on gene editing. When autophagy was triggered—either by nutrient ...

34. Liu X, Tang J, Peng L, Nie H, Zhang Y, and Liu P. Cancer-associated fibroblasts promote Malignant phenotypes of prostate cancer cells via autophagy: Cancer-associated fibroblasts promote prostate ...