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Of the 51 nasal M-IgA clones analyzed, they were classified into 11 groups based on their V-(D)-J usage, with the majority (83% ... of related antibodies originates from a common ancestor gene that ...

A clone was defined as having an identical CDR3 sequence and identical V and J gene assignments. Sequencing reads within a clone were grouped, and the clone size was calculated as the number of reads ...