In this post-hoc analysis, data were pooled from the randomised, placebo-controlled, phase 3 TULIP-1 (NCT02446912) and TULIP-2 (NCT02446899) trials of anifrolumab (300 mg intravenously once every 4 ...

Two methods are described for biasing conformational search during pharmacophore elucidation using a multiobjective genetic algorithm (MOGA). The MOGA explores conformation on-the-fly while ...