Christina Applegate is speaking candidly about her "really, really hard" battle with MS, describing it as the "worst thing I've ever had in my life." ...

Christina Applegate has had to deal with unkind speculation about how she might have contracted MS, as well as bizarre "cure" suggestions.

Christina Applegate got emotional on her podcast while announcing that her father recently died. 'This is the first time I've really cried,' she said.

Christina Applegate revealed in a new episode of her podcast that she has been hospitalized "upwards of 30 times" due to MS symptoms.

Christina Applegate says that she’s been in the hospital ‘upwards of 30 times’ because of diarrhea and vomiting ...

More than five years later, Christina Applegate is recalling how her struggle with multiple sclerosis (MS) began on the set of 'Dead to Me'.

Christina Applegate apologized on X after issuing fiery responses to people who challenged her viral reaction to Donald Trump‘s victory over Kamala Harris in the 2024 presidential election. The ...

Christina Applegate reunited with Ed O'Neill, who played her dad on "Married... with Children," on her "MeSsy" podcast.

Martyn LeNoble has been by Christina Applegate’s side for both her breast cancer diagnosis in 2008 and her multiple sclerosis battle ...

Christina Applegate’s Daughter Explains Her POTS Syndrome and Misophonia Condition on Podcast The close-knit mother and daughter discussed life dealing with chronic conditions and how they've ...