A research team has uncovered a novel molecular pathway linking oxidative stress to cell death in pig ovarian follicles, ...

A newly identified long noncoding RNA (lncRNA), named lnc2300, plays a protective role in ovarian granulosa cells but is ...

Dr. Roberta Lotti honoured for a pioneering work on PC111, reinforcing Scinai's strategic option agreement to acquire the ...

In a human-mouse xenogeneic GvHD (xGvHD) model, ALTB-268 significantly improved survival, reduced disease severity score and body weight loss, and decreased human CD4+ and CD8+ T cells, while ...

The studies suggest that mutant KRAS signals predominantly through the rapidly accelerating fibrosarcoma (RAF) effector pathway in pancreatic ductal adenocarcinoma (PDAC) models, with its ...

MicroRNAs (miRNA) are touted to be fundamental posttranscriptional regulators of gene expression. They are differentially regulated during health and disease states with a major impact on cellular ...

Apoptosis is a genetically controlled form of cell death mediated by enzymes called caspases, and GluR1-induced necrosis is associated with two batches of apoptotic cells. The first batch is found at ...

Abstract and Introduction Pathways to Caspase Activation and Apoptosis Effector Caspase Inhibition to Prevent Both Extrinsic and Intrinsic Signals Conclusion ...

EFFECTOR Therapeutics, a California-based biotech company that raised $325M for cancer treatments, has shut down without making any successful products.

Results Comparisons of caspase activity profiles demonstrated that the likelihood of colorectal tumours to undergo apoptosis decreases with advancing disease stage. Systems-level analysis correctly ...

Abstract and Introduction Pathways to Caspase Activation and Apoptosis Effector Caspase Inhibition to Prevent Both Extrinsic and Intrinsic Signals Conclusion References Pathways to Caspase ...