Caspase-3 activity has been described to be essential for drug-induced apoptosis. Recent results suggest that in addition to its downstream executor function, caspase-3 is also involved in the ...

OVCAR-3 cells were highly resistant to DOX-induced apoptosis ... that DOX-induced apoptosis was caspase-dependent in HUVECs and A2780 cells, whereas caspase-independent mechanisms seem to be ...

In turn, caspase 9 activates caspase 3. Smac/Diablo binds ... further caspase activation. Apoptosis-inducing factor and endonuclease G mediate caspase-independent cell-death pathways.

Impact of microsatellite instability status and sidedness of the primary tumor on immunophenotype of colorectal cancer. This is an ASCO Meeting Abstract from the 2018 ASCO Annual Meeting I. This ...