Cash runway extended into 2028; expected to enable multiple meaningful clinical data read-outs -- APOE program added to ...

Our findings revealed that LRP8, an apolipoprotein E receptor, is upregulated in BC patients with brain metastasis. Functional studies demonstrated that LRP8 knockdown significantly inhibited ...

EQ504 targets the aryl hydrocarbon receptor, a clinically validated pathway in the treatment of both skin and gastrointestinal diseases EQ504 has a unique, multi-modal, non-immunosuppressive mechanism ...

BACKGROUND: apoER2 (apolipoprotein E receptor-2) is a transmembrane receptor in the low-density lipoprotein receptor (LDLR) family with unique tissue expression. A single-nucleotide polymorphism that ...

Abraham: One of the primary ways the EEE virus causes damage is through two cell receptors, called very low-density lipoprotein receptor, or VLDLR, and apolipoprotein E receptor 2, or ApoER2.

Abraham: One of the primary ways the EEE virus causes damage is through two cell receptors, called very low-density lipoprotein receptor, or VLDLR, and apolipoprotein E receptor 2, or ApoER2.

Apolipoprotein E (APOE) is a protein that interacts with the angiotensin-converting enzyme receptor, essential for viral entry into the cell. Previous publications have suggested a possible role of ...

It includes all of the available Apo monomers for each of receptor and ligand, respectively, and all of the combinations with other monomer types. E.g., holo-receptor + apo-ligand1, AF2-receptor + apo ...