Research on centenarians reveals healthy aging involves genetic factors like APOE e2, balanced gut microbiomes, good sleep ...

As far as we know, no publications found significant associations between this disease's severity, OD, and APOE polymorphisms (E2, E3, and E4). Objective To analyze the epidemiology of OD and its ...

APOE genotypes and dementia risk: The article discusses the role of APOE e4 and e2 in Alzheimer's risk and cognitive preservation. The Apolipoprotein E (APOE) gene plays a role in the metabolism ...

In this review, we comprehensively, qualitatively, and critically synthesized several features of APOE-e2, a known APOE protective variant, including its associations with longevity, cognition, and ...

3 single nucleotide polymorphisms (SNPs): BDNF (rs6265), ACE (rs4291), and FAAH (rs324420), plus ApoE e4 and ApoE e2; a dopamine polygene score was also explored. Acute injury (infarct volume) and ...

There are three common forms of APOE – e2, e3 and e4, all distinct alleles that have varying risks of Alzheimer's Disease (AD). At one end of the spectrum is e2, which reduces risk of developing ...

The APOE gene has long been known to affect the risk of Alzheimer’s disease through its three main variants: E2 (low risk), E3 (intermediate risk), and E4 (high risk). More recently, a genetic ...

while carriers with a protective APOE e2 mutation had a delayed onset. Interestingly, the study also revealed that higher educational attainment was linked to preserved cognitive ability ...

while those with a protective APOE e2 mutation had delayed onset. Remarkably, higher educational attainment was associated with preserved cognitive function, even among those with the highest genetic ...

Hepcidin levels would be of interest as well. 2) How do the authors explain the iron-dependent effect of E2 on increasing atherosclerosis in the macrophage FPN KO ApoE KO mice since E2 appears to ...

Researchers believe the APOE gene is important in laying down myelin, which is a protein that insulates neurons in the brain. “If you happen to be lucky and get an E2 form of it, you have slight ...