NewAmsterdam Pharma’s push to show a cholesterol drug can prevent Alzheimer’s disease has passed another test. | NewAmsterdam ...

Using physically active transportation modes in midlife -- particularly cycling -- was tied to lower dementia risk and ...

Pre-specified analyses show that obicetrapib treatment leads to statistically significant and clinically meaningful reductions in the primary outc ...

Pre-specified analyses show that obicetrapib treatment leads to statistically significant and clinically meaningful reductions in the primary outcome measure of Alzheimer's disease biomarker in both ...

These cDCs present brain-derived antigens to T cells sitting in the cervical lymph nodes. In ApoE4 carriers, CD8+ T cells more easily cross from the blood into the brain. In tauopathy mice, antigens ...

2020). In the CNS, TIM3 is predominantly expressed by microglia, where it cranks up further in female ApoE4 carriers. Variants in the gene have been tied to AD risk (Sep 2021 news). By way of ...

Patients with Alzheimer disease and cognitive impairment with delayed REM sleep patterns have increased levels of brain amyloid and tau.

Unsurprisingly, it found that APOE4 carriers were likely to have more white matter loss; notably, however, those hewing to AHA lifestyles always showed reduced white matter loss regardless of ...

More morning naps were associated with a higher risk of Alzheimer's dementia, while more early afternoon naps were tied to reduced amyloid levels, data from the Rush Memory and Aging Project showed.

Many associations linking greater sedentary time with brain health and cognitive outcomes were present in APOE4 carriers but not in non-carriers, suggesting increased sedentary time may be ...

NewAmsterdam Pharma (NASDAQ: NAMS) has announced positive topline data from the prespecified Alzheimer’s disease ("AD") ...

Implementing these [suggested] recommendations will help ensure that ApoE4 carriers receive safe, effective, and personalized treatment strategies that reflect their unique medical needs. These ...