Anti-CD20 mAbs were originally created to treat B cell proliferative diseases such as non-Hodgkin's lymphoma and chronic ...

In diseases like Parkinson's and Alzheimer's, specific proteins misfold and clump together, forming toxic aggregates that ...

From preclinical research to regulatory approval and clinical adoption, diagnostic testing underpins every stage of ADC ...

Introduction Therapeutic antibodies are laboratory-engineered proteins designed to replicate the immune system's natural ability to combat dise ...

Researchers explore the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during ...

Single-dose administration of E6F6 could profoundly suppress the levels of hepatitis B surface antigen (HBsAg ... and only forms a smaller antibody–viral particle immune complex with limited ...

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism ...

Conversely, antibody depletion using beads conjugated with La, Jo-1 or U1-70 kD reduced the reactivity detected at the corresponding antigen features, but not reactivity detected at the Ro52 ...

Recombinant antibodies are invented antibodies formed by using recombinant DNA technology. While traditional monoclonal antibodies are derived from hybridoma technology, the recombinant antibodies are ...

The rules that govern antigen processing and presentation in DCs are complex. Numerous important cellular changes take place following exposure of DCs to TLR ligands. Although the pathways of ...

We're exploring the biochemical foundations of life. Without understanding how things work, we can’t fix them when they’re broken. In this day of modern diseases, this is critical. Fundamental science ...

A thyroglobulin antibody (TgAb) test looks for certain antibodies that attack the thyroid. The presence of TbAb in high levels may indicate that someone has an autoimmune condition. To conduct a ...