in terms of antigen-antibody complexes, a pathogenetic mechanism that would assume great importance 50–60 years later. Pirquet was born near Vienna in 1874. He studied theology in Innsbruck and ...

Once the excess reagent is removed by a five-minute incubation with nonspecific mouse IgG 1, the immune complexes are ready for use in ... In addition, the reagent will not obscure the primary ...

Determining how to predict the antibody-antigen interactions was the biggest challenge. The researchers focused on the ...

Anti-CD20 mAbs were originally created to treat B cell proliferative diseases such as non-Hodgkin's lymphoma and chronic ...

Thus, antigens can be bound to complement receptors even in the absence of complement-fixing antibody ... permitting the construction of immune complexes for presentation before the development ...

constructs retain the full complex of CD3 signaling but also have high antigen sensitivity via the fusion of an antibody binding domain. This hybrid receptor design combines the strengths of a CAR and ...