For potential candidates that act on the epigenome or chromatin-associated proteins, traditional gene expression assays are not sufficient to fully uncover the mechanism of action (MOA) or predict ...

How to Train Your Dragon filmmaker Dean DeBlois has a list of regrets about his movies, so found the live-action project a way to right some wrongs.

The enriched pathways, therefore, support the mechanism of action of both drugs, showing how the combined inhibition of BCL-2 and mitochondrial transcription creates a compounded cellular disruption ...

Theralase(R) Has Discovered a New Mechanism of Action in Its War on Cancer; Specifically, Ruvidar's(TM) Ability to Inhibit DeUbiquitinating Enzymes, an Important Class of Enzymes Which Have Been ...

The frequency of high blood glucose among patients receiving PI3K/Akt inhibitors to treat breast cancer has some oncologists wary about using the drugs at all.

The primary treatment for JME involves antiepileptic drugs (AEDs), which aim to restore the excitatory-inhibitory balance. These drugs function by modulating ion channels, enhancing GABAergic ...

The primary treatment for JME involves antiepileptic drugs (AEDs), which aim to restore the excitatory-inhibitory balance. These drugs function by modulating ion channels, enhancing GABAergic ...

This finding is consistent with 8-azaguanine’s known mechanism of action as an antimetabolite that resembles the purine base guanine (42) and reportedly the polyploid-specific disruptor of ...

The live-action remake of Disney’s Snow White, starring Rachel Zegler and Gal Gadot, hits theaters Friday. The film is the latest in a steady stream of remakes of original films into modernized ...

Previously known as JNJ-2113, icotrokinra (Protagonist Therapeutics, Johnson & Johnson) has a very specific mechanism of action for the treatment of moderate to severe plaque psoriasis, according ...

The article describes the mechanism of action of DM199 (rinvecalinase alfa), a recombinant form of human tissue kallikrein-1, and its scientific rationale in the Company’s ongoing Phase 2/3 ...