Antiepileptic drugs (AEDs) protect against seizures by modulation of voltage-gated sodium and calcium channels, enhancement of GABA A (γ-aminobutyric acid, type A) receptor-mediated synaptic ...

Lacosamide is a functionalized amino acid with a novel mechanism of action. Its antiepileptic activity is thought to be exerted via slow inactivation of voltage-gated sodium channels. [ 12 ] ...

This brief but important review discusses mechanisms of action of antiseizure drugs, with a focus on the newly approved lacosamide, and it also describes why some anti-seizure drugs actually cause ...

The mechanism of action of drug antagonists, blockers and inhibitors for these targets share the common feature that their mechanisms of action can be described by the two-step model in which the ...

Mechanism of action of two new synthetic drugs unravelled for the first time. ScienceDaily . Retrieved April 8, 2025 from www.sciencedaily.com / releases / 2015 / 04 / 150422084226.htm ...

An international research group has clarified the action mechanism of incretin-based drugs in the treatment of diabetes. The research group headed by Professor SEINO Susumu included Researcher ...